The Center for Integrated Biomolecular Communication (CIBC), led by James Takacs (Chemistry) and Concetta DiRusso (Biochemistry), serves to integrate the research activities of chemists, biochemists, engineers, and bioinformaticians to address critical knowledge gaps in our understanding of how cells communicate and integrate metabolic and regulatory pathways relevant to disease development and progression. CIBC investigators bring together unique expertise in the understanding of complex diseases and in the development of novel methodologies and technologies to probe communication pathways within and between cells and tissues.
The goals of the CIBC align with those of the Centers of Biomedical Research Excellence (COBRE) program at the National Institutes of Health . The objective of the COBRE initiative is to strengthen an institution’s biomedical research infrastructure through the establishment of a thematic multi-disciplinary center and to enhance the ability of investigators to compete independently for complementary National Institutes of Health (NIH) individual research grants or other external peer-reviewed support. (Info from: unlcms.unl.edu/cas/chemistry/integrative-biomolecular- communication/)
The CSI and its members serve as Directors of the Data Management and Analysis Core (DMAC) for the CIBC. The long-term objective of the DMAC is to establish a critical, sustainable resource for bioinformatics and analytical support, while its near-term goal is to develop and implement hardware, software, and expertise in high-throughput bio/chemical data, from multi-type data management to integrative statistical analyses.